University of Utah Post Doctoral Fellow in Salt Lake City, Utah


Open Date 05/04/2018

Requisition Number PRN17107B

Job Title Post Doc Res Assoc

Working Title Post Doctoral Fellow

Job Grade A00

FLSA Code Administrative

Patient Sensitive Job Code? No

Standard Hours per Week 40 hours

Full Time or Part Time? Full Time

Shift Day

Work Schedule Summary

M-F, 9am-5:30pm.

Special Work Requirements: Evenings and weekends may be necessary to fulfill experimental duties.

VP Area President

Department 01451 - HCI Mahesh Chandrasekharan Lab

Location Campus

City Salt Lake City, UT

Type of Recruitment External Posting

Pay Rate Range 20000 to 55000/DOE

Close Date

Open Until Filled Yes

Job Summary

The Chandrasekharan Laboratory, in the Department of Radiation Oncology at the University of Utah and Huntsman Cancer Institute, is searching for a highly motivated and hardworking postdoctoral researcher with prior experience in gene transcription or genome stability and epigenetic mechanisms, and the use of genomics-bioinformatics methodologies and mammalian experimental systems (cell culture and mouse model). The Chandrasekharan laboratory is focused on understanding epigenetic histone modifying mechanisms. We are seeking a post-doc to study the regulation and functions of histone modifying enzymes and their potential therapeutic targeting in cancers.

Experimental duties include, but are not limited to: creating knockout or knockin cell lines usingCRISPRgenome-editing technology; performing functional genomics or proteomics experiments and use bioinformatics for data analyses; overexpressing and purifying proteins or protein complexes using chromatography for proteomic, structural and/or biochemical/biophysical characterization studies; evaluating histone modifying enzyme functions in vivo in genetic mouse models; and performing preclinical drug-dosing studies in cell culture and in xenograft mouse models

Please see specific research projects and additional information pertaining to lab research on our website at:


The preferred candidate should have a Ph.D. in biomedical sciences, molecular-cell biology, or an allied area. Previous laboratory experience in mammalian cell culture and mouse model system, chromatography, genome editing, genomics and bioinformatics are required. The applicant should have a good working knowledge of protein biochemistry, epigenetics and chromatin biology, as well as bioinformatics and scientific writing skills. The ideal candidate will have demonstrated initiative, curiosity and dedication to scientific research as well as the ability to work independently and in a team environment. Essential Functions

1. CreateCRISPR-based knockin or knockout cell lines; perform epigenomics and bioinformatics, and conduct preclinical studies using in vitro or in vivo mammalian model systems.

2. Performs and directs specialized and complex lab tests, experiments and surgical procedures for studies.

2. Assists the Principal Investigator in the design, implementation and performance of new protocols and procedures as well as the modification of existing techniques.

3. Reviews scientific journals, abstracts and other literature for information concerning experimental procedures.

4. Makes advanced statistical calculations, analyzes data and prepares reports summarizing research results.

5. Operates complex and highly specialized laboratory and surgical instruments and equipment. Instructs others in their use.

6. Maintains an inventory of supplies, reagents, and samples used in procedures for the lab.

7. May supervise, train and review the work of laboratory personnel.

8. May prepare equipment and rooms for studies.

9. May assist with preparing grant proposals and budgets.

Problem Solving

Incumbents in this position work independently to review, analyze and interpret the results of the data collected and assist the principal investigator in getting the information presented to peers and published in appropriate journals. Incumbents in this position are responsible for addressing unusual or sensitive situations and for bringing them to resolution. If they are unable to bring them to resolution, they will consult with the principal investigator to obtain resolution.

This job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

Minimum Qualifications


Looking for a recent graduate with 0-1 year experience. Individuals from historically underrepresented groups, such as minorities, women, qualified persons with disabilities, and protected veterans are strongly encouraged to apply.

Type Benefited Staff

Special Instructions Summary

The University of Utah requires proof of PhD. Please attach copy of PhD, transcript, Letter stating received, etc. in applicant document other field.

List contact information for 2-3 references.

Additional Information

The University of Utah is an Affirmative Action/Equal Opportunity employer and is committed to diversity in its workforce. In compliance with applicable federal and state laws, University of Utah policy of equal employment opportunity prohibits discrimination on the basis of race or ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity/expression, veteran’s status, status as a qualified person with a disability, or genetic information. Individuals from historically underrepresented groups, such as minorities, women, qualified persons with disabilities, and protected veterans are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law.

To inquire about this posting, email: or call 801-581-2300. Reasonable accommodations in the application process will be provided to qualified individuals with disabilities. To request an accommodation or for further information about University AA/EO policies, please contact the Office of Equal Opportunity and Affirmative Action, 201 S. Presidents Cr., Rm 135, (801) 581-8365 (V/ TDD ), email: .

The University is a participating employer with Utah Retirement Systems (“URS”). To be eligible for retirement contributions, you must be hired into a benefit-eligible position. Certain new hires are automatically assigned to the URS retirement plan and other employees with prior URS service, may elect to enroll in the URS within 30 days of hire. Regardless of whether they are hired into a benefit-eligible position or not, individuals who previously retired and are receiving monthly retirement benefits from URS must notify the Benefits Department upon hire. Please contact Utah Retirement Systems at (801)366-7770 or (800)695-4877 or the University’s Benefits Department at (801)581-7447 for information.

This position may require the successful completion of a criminal background check and/or drug screen.