University of Utah Post Doctoral Fellow (E) in Salt Lake City, Utah

Details

Open Date 06/25/2018

Requisition Number PRN17591B

Job Title Post Doctoral Fellow (E)

Working Title Post Doctoral Fellow (E)

Job Grade A00

FLSA Code Administrative

Patient Sensitive Job Code? No

Standard Hours per Week 40

Full Time or Part Time? Full Time

Shift Day

Work Schedule Summary

Flexible.

VP Area U of U Health - Academics

Department 01502 - Department of Biochemistry

Location Campus

City Salt Lake City, UT

Type of Recruitment External Posting

Pay Rate Range DOE

Close Date

Open Until Filled Yes

Job Summary

We are currently looking for postdoctoral follows who are interested in

structure and mechanisms of membrane proteins. Interested

candidates are welcome to send his/her C.V. directly to Erhu Cao

(erhu.cao@biochem.utah.edu).

We are broadly interested in understanding atomic-scale

mechanisms of how membrane proteins function under normal and

diseased states. Membrane proteins play critical roles in nearly every

aspect of physiological processes that encompass relaying signals

between cells, transporting small molecules and ions across

membrane and catalyzing vital enzymatic reactions. Importantly,

membrane proteins constitute 60% of targets of currently approved

drugs and thus in-depth knowledge about their inner workings is

sorely needed to inform the development of effective therapeutic

strategies for treating various human diseases.

Our current research program focuses on structures, physiology,

pathology, and pharmacology of receptors, transporters, and ion

channels that play pivotal roles in the kidneys and, when malfunction,

cause various diseases in human. In one recent study, we

determined structures of the PKD2 channel, which, when mutated,

leads to development of polycystic kidney diseases (PKD) – a

common genetic disorder that affects 12.5 million patients worldwide.

Moreover, we are also interested in developing pharmacological tools

mainly for dissecting functions of ion channels and receptors, but also

as drug leads for developing novel therapeutic strategies. To achieve

these goals, we employ a multidisciplinary approach that includes

molecular biology, protein biochemistry, pharmacology, ion channel

electrophysiological, and X-ray crystallography and single-particle

electron cryo-microscopy (cryo-EM).

The University of Utah houses a state-of-the-art cryo-EM facility,

includingFEITitan Krios and TF20 microscopes, both of which are

equipped with a direct electron detector K2 camera. The University of

Utah is committed to become a world-class center for elucidating

fundamental biology by using cutting edge cryo-EM methodology.

Responsibilities

Lab work as directed.

Minimum Qualifications

Ph.D required

Preferences

Type Benefited Staff

Special Instructions Summary

Please apply online. For questions, please contact Erhu Cao directly at erhu.cao@biochem.utah.edu

Additional Information

The University of Utah is an Affirmative Action/Equal Opportunity employer and is committed to diversity in its workforce. In compliance with applicable federal and state laws, University of Utah policy of equal employment opportunity prohibits discrimination on the basis of race or ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity/expression, veteran’s status, status as a qualified person with a disability, or genetic information. Individuals from historically underrepresented groups, such as minorities, women, qualified persons with disabilities, and protected veterans are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law.

To inquire about this posting, email: employment@utah.edu or call 801-581-2300. Reasonable accommodations in the application process will be provided to qualified individuals with disabilities. To request an accommodation or for further information about University AA/EO policies, please contact the Office of Equal Opportunity and Affirmative Action, 201 S. Presidents Cr., Rm 135, (801) 581-8365 (V/ TDD ), email: oeo@umail.utah.edu .

The University is a participating employer with Utah Retirement Systems (“URS”). To be eligible for retirement contributions, you must be hired into a benefit-eligible position. Certain new hires are automatically assigned to the URS retirement plan and other employees with prior URS service, may elect to enroll in the URS within 30 days of hire. Regardless of whether they are hired into a benefit-eligible position or not, individuals who previously retired and are receiving monthly retirement benefits from URS must notify the Benefits Department upon hire. Please contact Utah Retirement Systems at (801)366-7770 or (800)695-4877 or the University’s Benefits Department at (801)581-7447 for information.

This position may require the successful completion of a criminal background check and/or drug screen.