Job Information

University of Utah Post Doc Res Assoc in Salt Lake City, Utah

Details

Open Date 06/30/2023

Requisition Number PRN35392B

Job Title Post Doc Res Assoc

Working Title Post Doc Res Assoc

Job Grade A00

FLSA Code Administrative

Patient Sensitive Job Code? No

Standard Hours per Week 40

Full Time or Part Time? Full Time

Shift Day

Work Schedule Summary

VP Area U of U Health - Academics

Department 00244 - Neurology

Location Campus

City Salt Lake City, UT

Type of Recruitment External Posting

Pay Rate Range 50000 to 70000

Close Date

Open Until Filled Yes

Job Summary

Postdoctoral position in the Pulst Laboratory to study neurodegenerative diseases using cell and animal models

We are looking for a motivated and creative scientist to join our group as a postdoctoral research associate/fellow to study the role of the ATXN2 protein/ RNA complex in neurodegeneration, specially in TDP43-mediated diseases like ALS , FTD , and LATE (Scoles et al, Nature 2017, Paul et al, Nature Com 2018) S.) pathological conditions using human stem cell-derived organoids (Wang et al., Nature Communications 2022).

We particularly welcome applications from recent or ready-to-graduatePh.D. students with backgrounds in molecular or cellular biology or from physician-scientists with a background in clinical aspects or neuropathology of neurodegenerative diseases

Responsibilities

  • Conduct experiments
  • Draft papers and grants

Minimum Qualifications

Preferences

Minimum qualification:

PhD or MD Degree

Type Benefited Staff

Special Instructions Summary

To apply, please send your CV and cover letter briefly describing your research interests and

motivation to Dr. Pulst (Stefan.pulst@hsc.utah.edu).

The following links provide more information about life in the Pulst lab:

http://healthcare.utah.edu/fad/mddetail.php?physicianID=u0595302

http://pulstlab.genetics.utah.edu/

Relevant publications:

Paul S et al: Staufen 1 links RNA stress granules and autophagy in model of neurodegeneration.

Nat Commun 9(1):3648 (2018)

Brown AS et al: MTSS1/Src family Kinase Dysregulation Underlies Multiple Inherited Ataxias.

Proc Natl Acad Sci USA 115(52); E12407-E12416 (2019)

Paul S et al: Staufen 1 in Human Neurodegeneration. Ann Neurol , 89(6), 1114-1128 (2021)

Gandelman M et al: Staufen 1 amplifies proapoptotic activation of the unfolded protein response.

Cell Death Differ . (10):2942-2951 (2020)

Scoles DR et al: A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS -associated gene ATXN2. J Biol Chem , 298(8), 102228. (2022)

Paul S et al: Staufen impairs autophagy in neurodegeneration. Ann Neurol . (2022)

Pulst et al: Effects of STAU1/staufen1 on autophagy in neurodegenerative diseases.

Autophagy. Jan 26:1-2 (2023)

Additional Information

The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service, may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules.

This position may require the successful completion of a criminal background check and/or drug screen.

The University of Utah values candidates who have experience working in settings with students and patients from all backgrounds and possess a strong commitment to improving access to higher education and quality healthcare for historically underrepresented students and patients.

All qualified individuals are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law. Upon request, reasonable accommodations in the application process will be provided to individuals with disabilities.

The University of Utah is an Affirmative Action/Equal Opportunity employer and does not discriminate based upon race, ethnicity, color, religion, national origin, age, disability, sex, sexual orientation, gender, gender identity, gender expression, pregnancy, pregnancy-related conditions, genetic information, or protected veteran’s status. The University does not discriminate on the basis of sex in the education program or activity that it operates, as required by Title IX and 34 CFR part 106. The requirement not to discriminate in education programs or activities extends to admission and employment. Inquiries about the application of Title IX and its regulations may be referred to the Title IX Coordinator, to the Department of Education, Office for Civil Rights, or both.

To request a reasonable accommodation for a disability or if you or someone you know has experienced discrimination or sexual misconduct including sexual harassment, you may contact the Director/Title IX Coordinator in the Office of Equal Opportunity and Affirmative Action ( OEO /AA). More information, including the Director/Title IX Coordinator’s office address, electronic mail address, and telephone number can be located at: https://www.utah.edu/nondiscrimination/

Online reports may be submitted at oeo.utah.edu

https://safety.utah.edu/safetyreport This report includes statistics about criminal offenses, hate crimes, arrests and referrals for disciplinary action, and Violence Against Women Act offenses. They also provide information about safety and security-related services offered by the University of Utah. A paper copy can be obtained by request at the Department of Public Safety located at 1658 East 500 South.