University of Utah Lab Specialist in Salt Lake City, Utah
Open Date 01/16/2019
Requisition Number PRN19388B
Job Title Lab Specialist
Working Title Lab Specialist
Job Grade D
FLSA Code Nonexempt
Patient Sensitive Job Code? No
Standard Hours per Week 40 hours
Full Time or Part Time? Full Time
Work Schedule Summary
VP Area President
Department 01154 - HCI Brad Cairns Lab
City Salt Lake City, UT
Type of Recruitment External Posting
Pay Rate Range 15.19 to 28.08
Open Until Filled Yes
A laboratory specialist position is available in the laboratory of Dr. Bradley Cairns, in collaboration with the Dr. Kevin Jones lab, in the Department of Oncological Sciences at the Huntsman Cancer Institute at the University of Utah. The Cairns lab studies how chromatin structure helps regulate gene transcription. The lab purifies and characterizes large protein complexes that useATPhydrolysis to remodel and modify chromosomal structure to regulate transcription. The lab uses genetic, biochemical, and genomic methods to understand the functions of these chromatin-regulatory complexes in living cells.
The successful candidate will assist in molecular cloning, the expression and purification of chromatin remodeling complexes, the preparation of chromatin substrates for use in biochemical assays, and the performance of assays related to the biochemical activities of purified chromatin remodeling complexes.
Experience with the production and purification of recombinant proteins is preferred, including basic molecular cloning, affinity purification, and chromatography. The successful candidate will aid in the development of technical procedures for a number of projects in the lab and present their contributions and progress at group meetings. Opportunities for authorship are available for contributions of figures to manuscripts.
•Basic molecular cloning
•Maintain tissue culture facility and cell lines
•Express recombinant proteins in bacterial and mammalian cells: perform plasmid transfections and harvest cells
•Purify recombinant proteins: perform cell fractionation, affinity purification, and size exclusion chromatography
•Assess concentration and purity of recombinant proteins with Bradford assays andSDS-PAGE
•Consistently produce recombinant proteins with a specified concentration and purity by strict adherence to detailed protocols
•PrepareDNAand chromatin templates for biochemical assays
•Perform assays related to the biochemical activities of purified proteins
•Share observations with co-workers and formulate suggestions to improve existing protocols and develop new techniques
The Lab Specialist assists in the development of research protocols and designs. Modifies and implements procedures. Records and interprets research results. The Lab Specialist works independently, under the general supervision of most senior laboratory personnel. Work may include training and supervising other laboratory personnel, who may refer sensitive or unusual situations to the Lab Specialist. Problems that cannot be resolved by the Lab Specialist will be referred to the most senior Lab personnel.
Work Environment and Level of Frequency that may be required:
Nearly Continuously: Office environment.
Often: Infectious disease, oils (there is air or skin exposure to oils or other cutting fluids), hazards (includes a variety of physical conditions, such as proximity to moving mechanical parts, moving vehicles, electrical current, working on scaffolding and high places, or exposure to chemicals).
Seldom: Exposure to animals.
Physical Requirements and Level of Frequency that may be required
Nearly Continuously: Hearing, listening, talking.
Often: Repetitive hand motion (such as typing), walking, standing, sitting.
Seldom: Bending, reaching overhead.
This job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.
Bachelor’s degree in Biology, Chemistry or other scientific discipline or equivalency; two years full-time laboratory experience; and demonstrated human relations and effective communication skills required. Working knowledge of advanced scientific techniques and procedures as well as the ability to make statistical calculations, analyze results, prepare reports and perform specialized tests also required.
Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.
•Bachelor’s degree or higher in biology, biochemistry, chemistry, or related field
•Experience with basic molecular cloning
•Experience with recombinant protein expression and purification
•Experience with affinity purification and chromatography
•Detail oriented and capable of performing accurate and reproducible work independently
•Works well in a team environment
Type Benefited Staff
Special Instructions Summary
The University of Utah is an Affirmative Action/Equal Opportunity employer and is committed to diversity in its workforce. In compliance with applicable federal and state laws, University of Utah policy of equal employment opportunity prohibits discrimination on the basis of race or ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity/expression, veteran’s status, status as a qualified person with a disability, or genetic information. Individuals from historically underrepresented groups, such as minorities, women, qualified persons with disabilities, and protected veterans are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law.
To inquire about this posting, email: firstname.lastname@example.org or call 801-581-2300. Reasonable accommodations in the application process will be provided to qualified individuals with disabilities. To request an accommodation or for further information about University AA/EO policies, please contact the Office of Equal Opportunity and Affirmative Action, 201 S. Presidents Cr., Rm 135, (801) 581-8365 (V/ TDD ), email: email@example.com .
The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service, may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules.
This position may require the successful completion of a criminal background check and/or drug screen.
The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with priorURSservice, may elect to enroll inURSif they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits fromURSare subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules.This position may require the successful completion of a criminal background check and/or drug screen.